KEGG   REACTION: R02101
Entry
R02101                      Reaction                               
Name
5,10-methylenetetrahydrofolate:dUMP C-methyltransferase
Definition
dUMP + 5,10-Methylenetetrahydrofolate <=> Dihydrofolate + dTMP
Equation
C00365 + C00143 <=> C00415 + C00364
Reaction class
RC00219  C00143_C00415
RC00332  C00364_C00365
Enzyme
2.1.1.45
Pathway
rn00240  Pyrimidine metabolism
rn00670  One carbon pool by folate
rn01100  Metabolic pathways
rn01232  Nucleotide metabolism
Module
M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45
     R02101  dUMP + 5,10-Methylenetetrahydrofolate <=> Dihydrofolate + dTMP
Orthology
K00560  thymidylate synthase [EC:2.1.1.45]
K13998  dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
Other DBs
RHEA: 12107

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (9)   
   KEGG PATHWAY (8)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
   SABIO-RK (1)   
Gene (7934)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (7932)   
All databases (7952)   

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